Analysis of Whole Genome of Indian Male Kashmiri Pandit

Remarkable advancement in next generation sequencing technology has made personal genome analysis feasible and affordable. Here we present the whole sequence of an individual from Kashmir region India who is pandit community (IHGP04). The Indian male’s was sequenced at 38.6 X coverage with a total 110 Gb data generated using Illumina HiSeq 2000 platform. variant revealed over 3.6 million single nucleotide variants 5 46 681 small insertions deletions including about 2.7 % novel (unreported) variants. known were analyzed for their health disease relevance drug pharmacogenetic profile. mitochondrial haplogroup (L3e2b1a1) indicative maternal ancestors’ arrival to subcontinent 70 000 y ago, while Y-chromosome (J) suggestive paternal ancestors less than 25 ago. haplogroups also suggest different routes used by arrive on subcontinent. validation relationship diseases should be logical step.